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The U.S. Food and Drug Administration (FDA) approved the first GLP-1 agonist (exenatide) in 2005. Researchers are still learning about their other potential uses and benefitsdapagliflozina vendo . GLP-1 agonists alone can’t treat Type 2 diabetes or obesity .. Both conditions require other treatment strategies, like lifestyle and dietary changes. There’s also a similar class of medications called dual GLP-1/GIP receptor agonists. . There’s currently one of these medications on the market. It’s called : Insulin is an essential hormone that allows your body to use the food you eat for energy. It lowers the amount of glucose (sugar) in your blood. If you don’t have enough insulin, your blood sugar increases, leading to is a hormone your body uses to raise your blood sugar levels when necessary. So, GLP-1 prevents more glucose from going into your bloodstream. GLP-1 agonist medications work by mimicking this hormone. In medication terms, an agonist is a manufactured substance that attaches to a cell receptor and causes the same action as the naturally occurring substance. In other words, GLP-1 medications bind to GLP receptors to trigger the effects (or roles) of the GLP-1 hormone. . The higher the dose of the GLP-1 agonist, the more extreme the effects. If you have Type 2 diabetes, the medications help manage your blood sugar by triggering your pancreas to release more insulin . . The slowed digestion also helps decrease blood sugar spikes. The satiety effect of GLP1-agonists reduces your food intake, appetite and hunger. These combined effects often result in weight loss.